Endocarditis in pregnancy and postpartum: cases in a prospective adult cohort and literature review

Objective: Pregnancy and postpartum infective endocarditis (PPIE), although uncommon, is a very serious condition. To describe cases of infectious (IE) in cohort adults with IE Brazilian center to review data from the recent literature on subject. Methods: Cases definite by modified Duke criteria were retrieved contemporary January 2006 December 2020. Literature topic was carried out case reports PPIE 2014 2020 compiled. Results: Two found 401 adult patients IE, prevalence 0.5% cohort, 2/139 (1.4%) among women 2/83 (2.4%) reproductive age (18 -49 years) this same cohort. The search for published resulted 61 episodes PPIE; these, 7 pregnant (11.4%), 10 fetuses (16.4%) 1 premature newborn (1.6%) died. There previous valve predisposition 12 (19.7%) intravenous drug use 14(23%). Left-sided valves most frequently affected 41 (67.2%) cases. common isolated agent methicillin sensitive Staphylococcus aureus 18/61 (29.5%) patients, as group, oral viridans streptococci accounted 16/61 (26.2%). Valve surgery done 70% patients. Conclusions: Intravenous remained be main risk factor IE. Mortality high mothers their children, despite fact more In fever without an obvious focus or post-partum women, diagnosis must readily considered, especially those prosthesis and/or use.